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The ‘Crispr-Cas9 revolution’ is set to change the world forever by enabling precise gene editing.
The science of editing genes to manipulate the code of life is now being rolled out to humans for the first time.
But the gene-editing techniques raise profound ethical questions and threats to human safety.
The ‘Crispr-Cas9 revolution’ is set to change the world forever by enabling precise gene editing. The science is being rolled out to humans for the first time. But the technology raises profound ethical and human safety questions and threats to our own existence.
The technology promises to cure genetic diseases and has already been successful in rodents and monkeys.
It could also make possible the development of human clones. The first attempt to edit the DNA of a human embryo was performed in July last year in South Korea.
The technique – Crispr-Cas9 – uses a ‘molecular scissors’ that snips out, or ‘edits’, a piece of DNA at the breakpoint of a gene, effectively ‘switching on’ the gene and turning it off or on.
The new technique is to be used on embryos to treat a wide range of diseases including sickle cell anaemia. But despite its huge promise, the technique raises profound ethical and human safety questions and threats to our own existence.
It could bring the prospect of eradicating diseases like Aids, or curing cystic fibrosis, sickle cell anaemia or haemophilia, and replacing faulty genes with the correct ones.
The approach could also eventually make possible the development of human clones.
But how will it be used, and what are the risks?
What is Crispr-Cas9?
It was developed in a Swiss laboratory in 2004 and is already used to edit genes in other species including fruit flies, goats and pigs. ac619d1d87
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